WHO 5th classification of Lymphoid neoplsm の履歴(No.2)

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• WHO 5th classification of Lymphoid neoplsm へ行く。
  • 1 (2022-07-16 (土) 09:15:19)
  • 2 (2022-07-16 (土) 16:06:32)
  • 3 (2022-07-16 (土) 23:10:09)
  • 4 (2022-07-17 (日) 06:17:35)

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Haematopathology-WHO 5th classification

WHO 5th Classification of Lymphoid classification†

2022年7月時点の文献--Leukemia;

Tumour-like lesions with B-cell predominance†

• Reactive B-cell-rich lymphoid proliferations that can mimic lymphoma *

• IgG4-related disease*

• Unicentric Castleman disease*

• Idiopathic multicentric Castleman disease*

• KSHV/HHV8-associated multicentric Castleman disease ( 4th Edでは, Multicentric Castleman disease

*; Not previously included in WHO 4th Ed

Precursor B-cell neoplasms†

B-cell lymphoblastic leukaemias/lymphomas []; WHO 4th Ed

• B-lymphoblastic leukaemia/lymphoma, NOS [Same]

• B-lymphoblastic leukaemia/lymphoma with high hyperdiploidy [B-lymphoblastic leukaemia/lymphoma with hyperdiploidy]

• B-lymphoblastic leukaemia/lymphoma with hypodiploidy　[Same]

• B-lymphoblastic leukaemia/lymphoma with iAMP21 [Same]

• B-lymphoblastic leukaemia/lymphoma with BCR::ABL1 fusion [B-lymphoblastic leukaemia/lymphoma with t(9;22)(q34;q11.2); BCR-ABL1]

• B-lymphoblastic leukaemia/lymphoma with BCR::ABL1-like features [B-lymphoblastic leukaemia/lymphoma, BCR-ABL1-like]

• B-lymphoblastic leukaemia/lymphoma with KMT2A rearrangement　[B-lymphoblastic leukaemia/lymphoma with t(v;11q23.3); KMT2A-rearranged]

• B-lymphoblastic leukaemia/lymphoma with ETV6::RUNX1 fusion [B-lymphoblastic leukaemia/lymphoma with t(12;21)(p13.2;q22.1); ETV6-RUNX1]]

• B-lymphoblastic leukaemia/lymphoma with ETV6::RUNX1-like features [Not previously included]

• B-lymphoblastic leukaemia/lymphoma with TCF3::PBX1 fusion [B-lymphoblastic leukaemia/lymphoma with t(1;19)(q23;p13.3); TCF3-PBX1]

• B-lymphoblastic leukaemia/lymphoma with IGH::IL3 fusion [B-lymphoblastic leukaemia/lymphoma with t(5;14)(q31.1;q32.1); IGH/IL3]

• B-lymphoblastic leukaemia/lymphoma with TCF3::HLF fusion [Not previously included]

• B-lymphoblastic leukaemia/lymphoma with other defined genetic abnormalities　[same]
   
   

Mature B-cell neoplasms†

Pre-neoplastic and neoplastic small lymphocytic proliferations

• Monoclonal B-cell lymphocytosis (Same)

• Chronic lymphocytic leukaemia/small lymphocytic lymphoma (Same)

• [B-cell prolymphocytic leukaemia]; Entity deleted

Splenic B-cell lymphomas and leukaemias

• Hairy cell leukaemia (Same)

• Splenic marginal zone lymphoma (Same)

• Splenic diffuse red pulp small B-cell lymphoma (Same)

• Splenic B-cell lymphoma/leukaemia with prominent nucleoli [Not previously included (encompassing hairy cell leukaemia variant and some cases of B-cell prolymphocytic leukaemia)]
   

Lymphoplasmacytic lymphoma

• Lymphoplasmacytic lymphoma [same]

Marginal zone lymphoma

• Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue [same]

• Primary cutaneous marginal zone lymphoma [Not previously included (originally included under “extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue”)]

• Nodal marginal zone lymphoma [same]

• Paediatric marginal zone lymphoma [same]